News

Recent publication: HEMOTION clinical trial protocol

Oct 19, 2022 – The protocol of the multicenter, randomized clinical trial HEMOTION (Hemoglobin transfusion threshold in traumatic brain injury optimization) has been published in the BMJ Open: https://bmjopen.bmj.com/content/12/10/e067117 The primary objective of this international pragmatic randomized open label blinded-endpoint trial is to evaluate whether a liberal (higher hemoglobin [Hb] threshold) versus a restrictive (lower… Read more »

Congratulations to Alexandre Bergeron for MSc thesis submission

Oct 5, 2022 – The Dean of the Faculty of Graduate and Postdoctoral Studies (FGPS), Mrs. Josée Bastien, congratulates Alexandre on the final submission of his master’s thesis (Master of Science in Epidemiology program with thesis, at Université Laval). We wish Alexandre all the success expected for his career.

Congratulations to Noémie Villemure-Poliquin on MSc thesis submission

Mar 3, 2022 – The Dean of the Faculty of Graduate and Postdoctoral Studies (FGPS), Mrs. Josée Bastien, congratulates Noémie on the final submission of her master’s thesis (Master of Science in Epidemiology program with thesis, at Université Laval). We wish Noémie all the success expected for her projects and research program.

Recent publication: lack of efficacy of convalescent plasma against COVID-19

Nov 22, 2021 – In a large international randomized clinical trial of more than 2,000 patients with COVID-19 and hospitalized in intensive care units worldwide, treatment with convalescent plasma showed a low likelihood of improving the number of days alive without organ support therapy. Read the publication in JAMA: https://jamanetwork.com/journals/jama/fullarticle/2784914 The publication in JAMA confirms… Read more »

Recent publication: Cognitive decline and blood pressure targets in the elderly

Nov 22, 2021 – The results of a systematic review exploring the association of intensive (ie, lower than usual) blood pressure (BP) reduction vs standard BP management with the incidence of cognitive decline and dementia in adults with hypertension have been published in JAMA: https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2786418 In summary: Current available evidence does not justify the use… Read more »

Recent publication: PROSPECT clinical trial

Oct 5, 2021 – The results of the randomized clinical trial PROSPECT (Probiotics to prevent Severe Pneumonia and Endotracheal Colonization Trial) have been published in JAMA: https://jamanetwork.com/journals/jama/article-abstract/2784358 In summary: Among critically ill patients requiring mechanical ventilation, administration of the probiotic L rhamnosus GG compared to placebo, resulted in no significant difference in the development of… Read more »

Hemotion trial: Highlights of Summer 2021

Sep 22, 2021 – Several milestones have been achieved over the last months: 50% enrollment has been reached; Two records were broken: in June, sites collectively enrolled 24 patients! Our previous monthly record was 22 patients; the Sunnybrook team randomized 6 patients in June. A first HEMOTION patient was enrolled in Brazil. We are grateful… Read more »

Recent publication: CONCOR-1 clinical trial

Sep 17, 2021 – The results of the randomized controlled trial CONCOR-1 (Convalescent Plasma for COVID-19 Respiratory Illness) have been published in Nature Medicine: https://www.nature.com/articles/s41591-021-01488-2 In summary: Convalescent plasma did not reduce the risk of intubation or death in hospitalized patients with COVID-19. However, the study also revealed that the antibody profile in the blood… Read more »

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