Oct 5, 2021 – The results of the randomized clinical trial PROSPECT (Probiotics to prevent Severe Pneumonia and Endotracheal Colonization Trial) have been published in JAMA: https://jamanetwork.com/journals/jama/article-abstract/2784358
In summary: Among critically ill patients requiring mechanical ventilation, administration of the probiotic L rhamnosus GG compared to placebo, resulted in no significant difference in the development of ventilator-associated pneumonia. These findings do not support the use of L rhamnosus GG in critically ill patients.
An article in ULaval – News is also available (in French):
Our clinical research team and several of our researchers including Dr. François Lauzier were involved in this clinical trial.