Improving the care of critically ill brain-injured and trauma patients

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Recent publication: PROSPECT clinical trial

Oct 5, 2021 – The results of the randomized clinical trial PROSPECT (Probiotics to prevent Severe Pneumonia and Endotracheal Colonization Trial) have been published in JAMA: In summary: Among critically ill patients requiring mechanical ventilation, administration of the probiotic L rhamnosus GG compared to placebo, resulted in no significant difference in the development of… Read more »

Hemotion trial: Highlights of Summer 2021

Sep 22, 2021 – Several milestones have been achieved over the last months: 50% enrollment has been reached; Two records were broken: in June, sites collectively enrolled 24 patients! Our previous monthly record was 22 patients; the Sunnybrook team randomized 6 patients in June. A first HEMOTION patient was enrolled in Brazil. We are grateful… Read more »

Recent publication: CONCOR-1 clinical trial

Sep 17, 2021 – The results of the randomized controlled trial CONCOR-1 (Convalescent Plasma for COVID-19 Respiratory Illness) have been published in Nature Medicine: In summary: Convalescent plasma did not reduce the risk of intubation or death in hospitalized patients with COVID-19. However, the study also revealed that the antibody profile in the blood… Read more »


Finding better ways to treat neurocritically ill patients

Our mission is to improve bedside management strategies and health outcomes of critically ill patients with traumatic brain injury, by carrying out patient-oriented research and implementing evidence-based informed decision-making.

The Chair

This Chair targets patient-oriented applied clinical research at the bedside of critically ill patients with traumatic brain injury.

Dr. Alexis F. Turgeon

Our team is specialized in clinical applied research focused on improving the care of critically ill patients with traumatic brain injury. The goal of our research is to improve bedside practices and health outcomes in this group of patients by using evidence-based, patient-centered decision-making. Our projects are carried out in collaboration with the Canadian Traumatic brain injury Research Consortium (CTRC), the Canadian Critical Care Trials Group (CCCTG), the Perioperative Anesthesia Clinical Trials Group (PACT) and other groups worldwide.