Improving the care of critically ill brain-injured and trauma patients

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Recent publication: lack of efficacy of convalescent plasma against COVID-19

Nov 22, 2021 – In a large international randomized clinical trial of more than 2,000 patients with COVID-19 and hospitalized in intensive care units worldwide, treatment with convalescent plasma showed a low likelihood of improving the number of days alive without organ support therapy. Read the publication in JAMA: The publication in JAMA confirms… Read more »

Recent publication: Cognitive decline and blood pressure targets in the elderly

Nov 22, 2021 – The results of a systematic review exploring the association of intensive (ie, lower than usual) blood pressure (BP) reduction vs standard BP management with the incidence of cognitive decline and dementia in adults with hypertension have been published in JAMA: In summary: Current available evidence does not justify the use… Read more »

Recent publication: PROSPECT clinical trial

Oct 5, 2021 – The results of the randomized clinical trial PROSPECT (Probiotics to prevent Severe Pneumonia and Endotracheal Colonization Trial) have been published in JAMA: In summary: Among critically ill patients requiring mechanical ventilation, administration of the probiotic L rhamnosus GG compared to placebo, resulted in no significant difference in the development of… Read more »


Finding better ways to treat neurocritically ill patients

Our mission is to improve bedside management strategies and health outcomes of critically ill patients with traumatic brain injury, by carrying out patient-oriented research and implementing evidence-based informed decision-making.

The Chair

This Chair targets patient-oriented applied clinical research at the bedside of critically ill patients with traumatic brain injury.

Dr. Alexis F. Turgeon

Our team is specialized in clinical applied research focused on improving the care of critically ill patients with traumatic brain injury. The goal of our research is to improve bedside practices and health outcomes in this group of patients by using evidence-based, patient-centered decision-making. Our projects are carried out in collaboration with the Canadian Traumatic brain injury Research Consortium (CTRC), the Canadian Critical Care Trials Group (CCCTG), the Perioperative Anesthesia Clinical Trials Group (PACT) and other groups worldwide.