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Dr. Ryan Zarychanski, MD, MSc, FRCPC

Associate Professor and Clinician-Scientist, Departments of Medicine and Community Health Sciences, University of Manitoba

Dr. Ryan Zarychanski is an Associate Professor and Clinician-Scientist, in the Departments of Medicine (Sections of Critical Care and of Hematology & Medical Oncology) and Community Health Sciences at the University of Manitoba in Winnipeg, Manitoba. Following subspecialty fellowships in Hematology and Critical Care Medicine, Dr. Zarychanski completed a Masters degree in Epidemiology and Community Health Sciences, and undertook a research fellowship at the University of Ottawa, Ontario.

Dr. Zarychanski’s research interests focus on the hematologic aspects of critical illness. Recent research includes evaluating processes of care in massive transfusion and investigating blood products and blood conservation in the critically ill.

Dr. Zarychanski is the Director of Knowledge Synthesis Unit at the Centre for Healthcare Innovation in Winnipeg, Manitoba and was awarded the Lyonel G. Israels Professorship in Hematology from the University of Manitoba in 2016 and the Canadian Institute of Health Research (CIHR) New Investigator Award in 2014.


Research Themes

Hematologic consequences of critical illness

Treatment of sepsis

Massive transfusion

Evidence-informed transfusion practices in acute care

Blood conservation

Systematic Reviews and Meta-analyses


Publications in PubMed

Active projects

“CanVECTOR (Canadian Venous Thromboembolism Clinical Trials and Outcomes Research) Network”. Canadian Institutes of Health Research (CIHR), Community Development Program Grant, co-investigator, 2015-2020.

“Tranexamic Acid during Cystectomy Trial (TACT)”. Canadian Institutes of Health Research (CIHR), Operating Grant, co-investigator, 2015-2018.

“Bleeding, transfusion, and the use of anticoagulants in patients with critical illness: Generating evidence to inform practice change and improve clinical outcomes”. Canadian Institutes of Health Research (CIHR), New Investigator Award, 2014-2019.

“Defining the burden and managing the effects of psychiatric comorbidity in chronic immunoinflammatory disease”. Canadian Institutes of Health Research (CIHR), co-investigator, 2014-2019.

“The George and Fay Yee Centre for Healthcare Innovation Program: Support for People and Patient-Oriented Research and Trials (SUPPORT) Units”. Canadian Institutes of Health Research (CIHR), Manitoba Health, Winnipeg Regional Health Authority (WRHA), University of Manitoba, co-investigator, 2014-2019.